Ricardo A. Verdugo, M.V., Ph.D.
Profesor Asistente
Programa de Genética Humana, ICBM
Facultad de Medicina, Universidad de Chile
raverdugo@uchile.cl+56 (2) 2978 9527

Educación

Ph.D. en Genética. Universidad de California, Davis, Diciembre de 2007.
Médico Veterinario, Universidad de Chile, Diciembre de 2001.
Licenciado en Medicina Veterinaria, Universidad de Chile, Diciembre de 1998.

Publicaciones seleccionadas

Treatment with Dexamethasone and Monophosphoryl Lipid A Removes Disease-Associated Transcriptional Signatures in Monocyte-Derived Dendritic Cells from Rheumatoid Arthritis Patients and Confers Tolerogenic Features. García-González, P. A., Schinnerling, K., Sepúlveda-Gutiérrez, A., Maggi, J., Hoyos, L., Morales, R. A., Mehdi, A. M., Nel, H. J., Soto, L., Pesce, B., Molina, M. C., Cuchacovich, M., Larrondo, M. L., Neira, Ó., Catalán, D. F., Hilkens, C. M., Thomas, R., Verdugo, R. A. and Aguillón, J. C. (2016), Frontiers in Immunology, 7, p. 458. doi: 10.3389/fimmu.2016.00458.

chromPlot: visualization of genomic data in chromosomal context. Oróstica KY, and Verdugo RA. Bioinformatics. 2016; btw137. doi:10.1093/bioinformatics/btw137

“Chapter 13: Visualization of Results from Systems Genetics Studies in Chromosomal Context.”, Orostica, Karen Y., and Ricardo A. Verdugo. 2017. In Systems Genetics – Methods and Protocols | Klaus Schughart | Springer, edited by Klaus Schughart and Robert W. Williams, 1st ed., 1488:283–97. Methods in Molecular Biology. Humana Press. http://www.springer.com/us/book/9781493964253.

SASH1, a new potential link between smoking and atherosclerosis. Weidmann H, Touat-Hamici Z, Durand H, Mueller C, Chardonnet S, Pionneau C, Charlotte F, Janssen K-P, Verdugo R, Cambien F, Blankenberg S, Tiret L, Zeller T, Ninio E. Atherosclerosis 2015, 242:571–579. doi: 10.1016/j.atherosclerosis.2015.08.013

Graphical Modeling of Gene Expression in Monocytes Suggests Molecular Mechanisms Explaining Increased Atherosclerosis in Smokers. Verdugo RA, Zeller T, Rotival M, Wild PS, Münzel T, Lackner KJ, Weidmann H, Ninio E, Trégouët DA, Cambien F, Blankenberg S, Tiret L.
PlosOne Journal 8(1):e50888. doi:10.1371/journal.pone.0050888

Using bioinformatics and systems genetics to dissect HDL cholesterol levels in an MRL/MpJ x SM/J intercross. Leduc M.S., Hageman Blair R.S., Verdugo R.A., Tsaih S., Walsh K., Churchill G.A., Paigen B. 2012.
Journal of Lipid Research, 53(6):1163-1175. doi:10.1194/jlr.M025833.

Genetic analysis of complex traits in the emerging collaborative cross. Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, et al. 2011. Genome Research (March 15). doi:10.1101/gr.111310.110.

Serious limitations of the QTL/Microarray approach for QTL gene discovery. Verdugo, R.A., Farber, C.R., Warden, C.H., and Medrano, J.F.
BMC Biology 2010, 8:96. doi:10.1186/1741-7007-8-96.

Importance of Randomization in Microarray Experimental Designs with Illumina Platforms, Verdugo, R.A., Deschepper, C., Muñoz, G. Pomp D., and Churchill, C.A.
Nucleic Acids Research 2009, 37(17): 5610-5618. doi:10.1093/nar/gkp573.

Comparison of Gene Coverage of Mouse Oligonucleotide Microarray Platforms.
Verdugo, R. A. and J. F. Medrano.
BMC Genomics 2006, 7:58 . doi:10.1186/1471-2164-7-58.

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